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Women With IC More Likely to Have Cystitis Glandularis, Chinese Study Suggests

Zhang W, Yao YS, Lin ME, Xie WJ, Pan WW. Unexplained association between cystitis glandularis and interstitial cystitis in females: a retrospective study. Int Urogynecol J. 2015 Aug 1. [Epub ahead of print]

This report is from a group of Chinese investigators who say they have observed an increase in the number of women with interstitial cystitis (IC) who also have cystitis glandularis (CG), a type of small and likely benign lesion commonly found in bladder biopsies. The investigators reviewed nearly 400 patient charts and found that the patients with IC were more likely to have CG compared with women in the general population (i.e. women without IC). Moreover, about 65% of the women with both IC and CG had other obstructive lower urinary tract diseases, compared with only about 44% of women with IC but no CG. Although CG is generally considered benign, some experts say patients with CG should be monitored because there have been some reports of a potential association between CG and bladder cancer.