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Literature Reviews>Etiology

Research Illustrates Multiple Underlying Factors Contributing to Development of IC/BPS

Jhang JF, Kuo HC1. Pathomechanism of Interstitial Cystitis/Bladder Pain Syndrome and Mapping the Heterogeneity of Disease. Int Neurourol J. 2016 Nov;20(Suppl 2):S95-104. Epub 2016 Nov 22. This educational article includes…

Brain Study Provides Insights on How Women With IC Process Bladder Sensations

Deutsch G, Deshpande H, Frölich MA2, Lai HH, Ness TJ. Bladder Distension Increases Blood Flow in Pain Related Brain Structures in Subjects with Interstitial Cystitis. J Urol. 2016 Sep;196(3):902-10. doi:…

Mast Cells, Associated With Inflammation and Allergies, May Be Implicated in IC/BPS

Regauer S. Mast cell activation syndrome in pain syndromes bladder pain syndrome/interstitial cystitis and vulvodynia. Transl Androl Urol. 2016 Jun;5(3):396-7. doi: 10.21037/tau.2016.03.12. A mast cell is a type of white…

IgE Antibodies Play a Role in Development of Ulcerative IC, Research Suggests

Jhang JF, Hsu YH, Jiang YH, Kuo HC. The Role of Immunoglobulin E in the Pathogenesis of Ketamine Related Cystitis and Ulcerative Interstitial Cystitis: An Immunohistochemical Study. Pain Physician. 2016…

Microbiome May Provide Clues to IC/BPS Diagnosis and Treatment

Braundmeier-Fleming A, Russell NT, Yang W, Nas MY, Yaggie RE, Berry M, Bachrach L, Flury SC, Marko DS, Bushell CB, Welge ME, White BA, Schaeffer AJ, Klumpp DJ. Stool-based biomarkers…

Urinary Cations: Implicated as Potential Cause of Bladder Dysfunction in Male IC/BPS Patients

Argade S, Berecz Z, Su Y, Parsons CL. Increased toxic urinary cations in males with interstitial cystitis: a possible cause of bladder symptoms. World J Urol. 2016 Mar 30. [Epub…

Diet Choices and Lifestyle Factors Implicated In Men With Chronic Pelvic Pain

Chen X, Hu C, Peng Y, Lu J, Yang NQ, Chen L, Zhang GQ, Tang LK, Dai JC. Association of diet and lifestyle with chronic prostatitis/chronic pelvic pain syndrome and…

Infrequent Coffee Drinkers May Be Most Vulnerable to Effects of Coffee on Urinary Symptoms

Staack A, Distelberg B, Schlaifer A, SabatĂ© J. Prospective study on the effects of regular and decaffeinated coffee on urinary symptoms in young and healthy volunteers. Neurourol Urodyn. 2015 Dec…