News & Blog
TRPV1-Targeted Gene Therapy: Novel Treatment for IC/BPS?
Majima T, Funahashi Y, Takai S, Goins WF, Gotoh M, Tyagi P, Glorioso JC, Yoshimura N. Herpes Simplex Virus Vector-Mediated Gene Delivery of Poreless TRPV1 Channels Reduces Bladder Overactivity and…
Cis-Urocanic Acid: Novel Treatment Option for Inflammatory Bladder Conditions?
Konkol Y, Bernoulli J, Streng T, Jääskeläinen K, Laihia J, Leino L. Intravesical treatment with cis-urocanic acid improves bladder function in rat model of acute bladder inflammation. Neurourol Urodyn. 2015…
Hyaluronic Acid May Be Effective as a Potential Treatment for Interstitial Cystitis
Rooney P, Srivastava A, Watson L, Quinlan LR, Pandit A3. Hyaluronic acid decreases IL-6 and IL-8 secretion and permeability in an inflammatory model of interstitial cystitis. Acta Biomater. 2015 Jun;19:66-75.…
Novel Immunotherapy Shows Promise in Preclinical Studies of IC-Related Bladder Pain
DeBerry JJ, Saloman JL, Dragoo BK, Albers KM, Davis BM. Artemin Immunotherapy Is Effective in Preventing and Reversing Cystitis-Induced Bladder Hyperalgesia via TRPA1 Regulation. J Pain. 2015 Jul;16(7):628-36. doi: 10.1016/j.jpain.2015.03.014.…
Researchers Link IC/BPS Tissue Impairment to Expression of Prostaglandin E2
Marentette JO, Hurst RE, McHowat J. Impaired Expression of Prostaglandin E2 (PGE2) Synthesis and Degradation Enzymes during Differentiation of Immortalized Urothelial Cells from Patients with Interstitial Cystitis/Painful Bladder Syndrome. PLoS…
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