News & Blog
Platelet-Rich Plasma Instillation Does Not Suppress IC-Related Findings in Rats
Ozyuvali E, Yildirim ME, Yaman T, Kosem B, Cimentepe E. Protective Effect of Intravesical Platelet-Rich Plasma on Cyclophosphamide-Induced Hemorrhagic Cystitis. Clin Invest Med. 2016 Dec 1;39(6):27524. Although a recent basic…
Spinal Nerve Cells May Play a Role in Pain Related to IC/BPS
Liu B, Su M, Tang S, Zhou X, Zhan H, Yang F, Li W, Li T, Xie J. Spinal astrocytic activation contributes to mechanical allodynia in a rat model of…
Drugs That Block mTOR Might Reduce Pain and Bladder Hyperactivity
Liang S, Li J, Gou X, Chen D. Blocking mammalian target of rapamycin alleviates bladder hyperactivity and pain in rats with cystitis. Mol Pain. 2016 Oct 25;12. pii: 1744806916668868. Print…
Targeting ICAM-1 May Reduce Bladder Inflammation in IC/BPS, Rat Study Shows
Zhang X, He H, Lu G, Xu T, Qin L, Wang X, Jin X, Liu B, Zhao Z, Shen Z, Shao Y. Specific inhibition of ICAM-1 effectively reduces bladder inflammation…
Platelet-Rich Injections, From Patient’s Own Blood, May Hold Promise in Future for IC/BPS
Dönmez MÄ°, Ä°nci K, Zeybek ND, DoÄźan HS, Ergen A. The Early Histological Effects of Intravesical Instillation of Platelet-Rich Plasma in Cystitis Models. Int Neurourol J. 2016 Sep;20(3):188-196. Epub 2016…
Researchers Pinpoint Two Inflammation-Related Genes Potentially Implicated in IC/BPS
Offiah I, Didangelos A, Dawes J, Cartwright R, Khullar V, Bradbury EJ, O’Sullivan S, Williams D, Chessell IP, Pallas K, Graham G, O’Reilly BA, McMahon SB. The Expression of Inflammatory…
Hyberbaric Oxygen Therapy May Enhance Healing in IC/BPS
Yilmaz M, Cakmak T, Yenilmez A, Baseskioglu B, Metin S. Effects of hyperbaric oxygen therapy on hydrochloric acid-induced interstitial cystitis in rats: a histological and ultrastructural study. Undersea Hyperb Med.…
Targeting PACAP Shows Promise in Study of Mice with Bladder Dysfunction
Girard BM, Malley SE, Mathews MM, May V, Vizzard MA. Intravesical PAC1 Receptor Antagonist, PACAP(6-38), Reduces Urinary Bladder Frequency and Pelvic Sensitivity in NGF-OE Mice. J Mol Neurosci. 2016 May…