News & Blog

Month: March 2016

Bladder Pain Linked to Changes in Brain Function

Sadler KE, Kolber BJ. Urine trouble: Alterations in brain function associated with bladder pain. J Urol. 2016 Feb 20. pii: S0022-5347(16)00365-7. doi: 10.1016/j.juro.2015.10.198. [Epub ahead of print] The authors of…

JNK Pathway Could Be Implicated in Development of IC/BPS

Zhao J, Wang L, Dong X, Hu X, Zhou L, Liu Q, Song B, Wu Q, Li L. The c-Jun N-terminal kinase (JNK) pathway is activated in human interstitial cystitis…

Quitting Smoking Can Help Reduce IC Symptoms

Mobley D, Baum N. Smoking: Its Impact on Urologic Health. Rev Urol. 2015;17(4):220-5. In this educational article for physicians and patients, the authors describe a variety of urologic conditions that…

Best Approach to Managing Bladder Pain: Patient Centered and Collaborative Approach

Speer LM, Mushkbar S, Erbele T. Chronic Pelvic Pain in Women. Am Fam Physician. 2016 Mar 1;93(5):380-7. In this article, aimed at providing practical recommendations for family physicians to follow,…

Middle-Aged Women With IC May Be at Higher Risk of Hysterectomy

Lee MH, Chang KM, Wu SL, Lin HH, Lin HY, Wu HC. A cohort study of interstitial cystitis/bladder pain syndrome and hysterectomy. Int Urogynecol J. 2016 Mar 4. [Epub ahead…

Female Urologic Pain in Adulthood May Be Related to Stresses Early in Life

Pierce AN, Di Silvestro ER, Eller OK, Wang R, Ryals JM, Christianson JA. Urinary bladder hypersensitivity and dysfunction in female mice following early life and adult stress. Brain Res. 2016…

Hormone Used to Treat Infertility May Be a Potential Treatment Option for IC/BPS

Rao CV. Therapeutic Potential of Human Chorionic Gonadotropin Against Painful Bladder Syndrome/Interstitial Cystitis. Reprod Sci. 2016 Mar 22. pii: 1933719116639139. [Epub ahead of print] Human chorionic gonadotropin (HCG) is a…

Novel Drug AQX-1125 Shows Early Promise in Moderate to Severe IC/BPS

Nickel JC, Egerdie B. Davis E, Evans R, Mackenzie L, Shrewsbury SB. A Phase II Study of Efficacy and Safety of a Novel, Oral SHIP1 Activator, AQX-1125, in Subjects with…

Meditation May Have Unique and Synergistic Pain-Relieving Properties, Investigators Say

Zeidan F, Adler-Neal AL, Wells RE, Stagnaro E, May LM, Eisenach JC, McHaffie JG, Coghill RC. Mindfulness-Meditation-Based Pain Relief Is Not Mediated by Endogenous Opioids. J Neurosci. 2016 Mar 16;36(11):3391-7.…

Bladder Instillation of Liposomes Promising in Patients With IC/BPS

Janicki JJ, Chancellor MB, Kaufman J, Gruber MA, Chancellor DD. Potential Effect of Liposomes and Liposome-Encapsulated Botulinum Toxin and Tacrolimus in the Treatment of Bladder Dysfunction. Toxins (Basel). 2016 Mar…